WebDec 8, 1995 · Genes from Drosophila melanogaster have been identified that encode proteins homologous to Orc2p and Orc5p of the Saccharomyces cerevisiae origin … Webwith Saccharomyces cerevisiae origins involves four of the six subunits (Orc1p, Orc2p, Orc4p, and Orc5p) recognizing the 11-bp autonomous replicating sequence (ARS) consensus sequence (ACS) as well as several less well-defined adjacent DNA sequences including a subset of B1 element sequences (Bell 2002).
Cell cycle-dependent localization of Orc2p and Mcm7p at human ...
WebThe histograms (right) show ChIP enrichment of Orc2p and Mcm7p at the MCM4 and ori6 origins during the different stages of the cell cycle. The data shown are the mean values and standard ... WebORC2p (the protein product of the gene) is a subunit of the Origin Recognition Complex (ORC), which is essential for initiation of DNA replication. Cells bearing the orc2-1 mutation are defective in the initiation of replication, and these cells die much more rapidly than wild-type cells. As they die, they exhibit many of the signature symptoms ... mice sheffield
RNAP-II molecules participate in the anchoring of the ORC to
WebThe Saccharomyces cerevisiae Orc2 protein is a subunit of the origin recognition complex, ORC, which binds in a sequence-specific manner to yeast origins of DNA replication. With … WebDec 8, 1995 · Science. Volume 270 . Issue 5242 . 8 Dec 1995. MSL-2 is a male-specific protein in Drosophila that binds to hundreds of sites along the single male X chromosome and increases gene expression to match that of the two X chromosomes in females. When this protein is ectopically expressed in females, as shown in this immunofluorescence … WebMicrosequencing of the 43- and 48-kDa proteins that copurified with Orc1p and Orc2p led to their identification as the Orc4p and Orc5p subunits, respectively. Peptide sequences from … mice server port 5022