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Refractoriness medical definition

WebApr 12, 2024 · The refractory period is the time after an action potential is generated, during which the excitable cell cannot produce another action potential. There are two subphases of this period, absolute and relative refractoriness. Absolute refractoriness overlaps the depolarization and around 2/3 of repolarization phase. WebSep 22, 2016 · An International Working Group (IWG) defined refractory ITP as disease that does not respond to or relapses after splenectomy and that requires treatment to reduce the risk of clinically significant bleeding. 2 The American Society of Hematology ITP Guidelines endorsed this definition as a means of identifying the most severely affected patients. …

Refractory disease - definition of Refractory ... - The Free Dictionary

Webrefractory: See: contumacious , difficult , disobedient , disorderly , fractious , froward , hostile , incorrigible , indomitable , inflexible , insubordinate ... Webre·frac·to·ry ( rĕ-frak'tŏr-ē) 1. Resistant to treatment, as of a disease. Synonym (s): intractable (1) , obstinate (2) . 2. Synonym (s): obstinate (1) . [L. refractarius, fr. refringo, pp. -fractus, to break in pieces] Medical Dictionary for the Health Professions and Nursing © Farlex 2012 re·frac·to·ry ( rĕ-frak'tŏr-ē) how to download brushes for medibang https://teachfoundation.net

Refractory - definition of refractory by The Free Dictionary

WebAug 28, 2014 · It is still being debated what should be the key parameter of a definition of refractoriness (e.g., unresponsiveness to treatment, high frequency, severe disability or all of these features) ... medical cost reimbursement, screening tool for invasive treatment or implantable devices. With the need of minimizing the risk of a misdiagnosis we ... WebJul 20, 2015 · Definition Platelet refractoriness can represent a significant clinical problem that complicates provision of platelet transfusions, and which may be associated with adverse clinical outcomes and increased health care costs. WebImportantly, refractoriness in cells with reduced E m can outlast voltage recovery of the action potential (i.e., the cell can still be refractory or partially refractory after the resting E m returns to its most negative value). View chapter Purchase book Temperature and Excitable Membranes☆ M. Vornanen, in Reference Module in Life Sciences, 2024 how to download browser videos

Refractoriness definition of refractoriness by Medical dictionary

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Refractoriness medical definition

Excitability - an overview ScienceDirect Topics

WebDictionary FastHealth Email This! re·frac·to·ri·ness n : the insensitivity to further immediate stimulation that develops in irritable and esp. nervous tissue as a result of intense or … Webdis·ease (dĭ-zēz′) n. 1. An abnormal condition of a part, organ, or system of an organism resulting from various causes, such as infection, inflammation, environmental factors, or …

Refractoriness medical definition

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WebRefractoriness is one of the factors limiting the frequency of recurrence of biological signals, their summation, and the speed at which they are transmitted. The duration of refractory periods may be altered by changes in temperature or the … WebRefractoriness. a short-term decrease in the excitability of nervous or muscle tissue occurring immediately after the manifestation of action potential. It can be detected by …

WebHeart Muscle Refractory Period. The effective refractory period (ERP) is the longest premature coupling interval (S1-S2) at a designated stimulus amplitude (usually 2× diastolic threshold) that results in failure of propagation of the premature impulse through a tissue. From: Clinical Arrhythmology and Electrophysiology, 2009. WebMar 11, 2024 · The International Myeloma Working Group (IMWG) has published new guidelines for the treatment of patients with relapsed or refractory (resistant to treatment) myeloma in the March 2024 issue of The Lancet Oncology. Authored by the world’s top myeloma experts, this manuscript analyzes the results of phase II and III clinical trials and …

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WebThe meaning of REFRACTORINESS is the insensitivity to further immediate stimulation that develops in irritable and especially nervous tissue as a result of intense or prolonged stimulation. the insensitivity to further immediate stimulation that develops in irritable … Synonyms for REFRACTORINESS: rebellion, recalcitrance, rebelliousness, …

WebIn conclusion, platelet transfusion refractoriness requires 2 or more inappropriate responses to platelets as defined by below normal PPR or CCI. Platelet transfusion refractoriness is … how to download bses yamuna billWebPlatelet transfusion refractoriness. Platelet transfusion refractoriness is the repeated failure to achieve the desired level of blood platelets in a patient following a platelet transfusion. … least overhead antivirusWebadj. 1. Showing or characterized by obstinate resistance to authority or control: refractory children; refractory behavior. 2. Difficult to melt or work; resistant to heat: a refractory … how to download brushes on clip studioWebDec 4, 2024 · Refractoriness can be caused by immune and nonimmune factors, with nonimmune factors responsible for 60% to 80% of cases. 1 Immune factors, which play a … least paid jobs in indiaWebDec 4, 2024 · Most studies define refractoriness as a CCI of <5,000 after 2 sequential transfusions. 2 However, a CCI of <7,500 or a PPR of <30% are also accepted values. 6 Figure 1. View large Download PPT Formulae used in the diagnosis of platelet refractoriness. 5 Confirming immune-based refractoriness how to download brytewave booksWebre·frac·to·ry (rĭ-frăk′tə-rē) adj. 1. Showing or characterized by obstinate resistance to authority or control: refractory children; refractory behavior. 2. Difficult to melt or work; resistant to heat: a refractory material such as silica. 3. Resistant to treatment: a refractory case of acne. n. pl. re·frac·to·ries One that is refractory ... how to download brushes on procreateWebExcitability is inversely related to the charge required for excitation. Excitability of a cardiac cell depends on the passive and active properties of the cell membrane. The passive … least painful area for tattoo